SARSCoV2, COVID-19 and the Variants #2

Multiple Defenses against COVID

Our immune system sports more defenses against COVID-19 than just antibodies.  While the experts lose sleep over whether vaccines and antibodies will work against new strains, our amazing immune system offers more options.  Researchers at La Jolla Institute remind us that the immune system uses T Cells to target other viral structures besides the spike protein in defending our bodies against the virus.  Read the article for more information and look back at my main article on the subject of variants.


Original Article:

Alison Tarke, John Sidney, Conner K. Kidd, Jennifer M. Dan, Sydney I. Ramirez, Esther Dawen Yu, Jose Mateus, Ricardo da Silva Antunes, Erin Moore, Paul Rubiro, Nils Methot, Elizabeth Phillips, Simon Mallal, April Frazier, Stephen A. Rawlings, Jason A. Greenbaum, Bjoern Peters, Davey M. Smith, Shane Crotty, Daniela Weiskopf, Alba Grifoni, Alessandro Sette. Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases. Cell Reports Medicine, 2021; 100204 DOI: 10.1016/j.xcrm.2021.100204

Thanks to Science Daily:

La Jolla Institute for Immunology. “T cells can mount attacks against many SARS-CoV-2 targets — even on new virus variant: New research gives detailed look at vulnerable sites on the novel coronavirus — beyond the receptor binding domain.” ScienceDaily. ScienceDaily, 27 January 2021. <www.sciencedaily.com/releases/2021/01/210127140137.htm>.

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